Scoped Trail Carbine- that weapon's just awesome.
Brush Gun- for indoors fighting, sneaky Deathclaws, cloaked Nightkin and any other big tough close-range surprises. It's nice to be able to end 99% of fights with a single well-placed shot.
Fully modded 10mm Pistol- for stealth kills, like taking out the Legion guards who take away your weapons at Fortification hill.
1st Recon beret- because of the 5% crit chance. It's the best hat in the game unless you're playing Explosives-only.
Vault 34 Security Armor- Highest DT light armor in the game unless you have Dead Money. Easily damaged, but with Jury Rigging you can repair it by any suit of clothes you find.
My usual travel weight is around 30-35lbs with Pack Rat. The travel weight includes two Weapon Repair Kits or BB guns, and 2 lightweight suits of clothing, for emergency repairs.